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OCR: Hemoglobin 2 x-globin polypeptides [ 141 amino acids each 1 2B-globin polypeptides ( 146 amino acids each Heme group «-globin( 141 amino acids] : no differences in sickle-cell anemia. ß-globin ( 146 amino acids) : single amino acid change in sickle-cell anemia Normal cells: 1 2 3 4 5 6 7 val-his-leu-thr-pro-glu-glu ... 1 2 3 4 5 6 7 HbS [sickle cells) : val-his-leu-thr-pro-val-glu ...